Successful treatment of acute oral copper sulfate poisoning: a case report
Abstract
The incidence of copper sulfate poisoning varies across different regions. It is relatively rare in Western countries but more prevalent in South Asian nations, accounting for approximately 40% of all heavy metal poisoning cases. The majority of affected individuals are rural residents, with a mortality rate ranging from 14% to 36%. Copper sulfate poisoning often leads to gastrointestinal corrosion, intravascular hemolysis, hemolytic anemia, methemoglobinemia, and acute multi-organ dysfunction, often resulting in death due to delayed treatment. In June 2024, we successfully managed a case of acute oral copper sulfate poisoning through early interventions, including gastric lavage and sodium dimercaptopropane sulfonate (Na-DMPS) for copper chelation, resulting in the patient's recovery and discharge after 1 week.
The paper
Tianjin Medical University General Hospital
Frontiers in Pharmacology, 6 Aug 2026
