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Science

Signatures of aging and disease in a single organelle

By Jeeyoon Na, Anne Brunet
CommentaryMechanisms
Paper
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Abstract

Changes in lysosomal metabolites are associated with both aging organs and lysosomal storage diseases.

  • Lysosome
  • Lysosomal metabolites

The paper

Jeeyoon Na, Anne Brunet

Institute for Stem Cell Biology and Regenerative Medicine; Stanford University

Science, 30 Jul 2026

doi.org/10.1126/science.aej5901PubMed 42531418

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