Glucose and Lipid Metabolic Mechanisms in Vascular Aging and Related Therapeutic Strategies

Vascular aging represents an independent risk factor for vascular disorders, with underlying cellular and molecular mechanisms closely associated with metabolic dysfunction, particularly disturbances in glucose and lipid metabolism. Therefore, understanding the interplay between disorders in glucose and lipid metabolism, as well as vascular aging, is crucial for preventing vascular disease. Early clinical recognition and targeted intervention are essential for the diagnosis and management of vascular senescence-related conditions. This review evaluates the metabolic mechanism underlying vascular aging, highlights clinical biomarkers and assessment strategies, and summarizes timely therapeutic approaches aimed at improving metabolic function.