Preprint

SIEP-PDS v1: Pre-registered 74-pathway substrate for the neurodegeneration–cancer inverse comorbidity SNBE analysis

Preprint: study protocolAI & data
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Abstract

This OSF project hash-freezes the analytical substrate (74-pathway scaffold + 25 literature priors, frozen 2026-05-12 UTC) of an aging-myeloid-cell SNBE analysis quantifying the neurodegeneration-cancer inverse comorbidity. Accompanies Lin W. et al., Nature Aging submission v3.2 (2026-05-19). Substrate SHA-256: pathway_set_v1.json = 0f978ae046c2e1a30572ddcda29e15da6038fb434690669716a5fcf6e3abeb5f; Supp_Tab_S2_74pathway_priors.csv = e2f7f35d5caaa8aeaeeb2800de81581593ef0e8bf07ec4fb1fdd59dae1f2719d.