The Relationship Between Biological Aging with Interdisciplinary Health Indicators: A Scoping Review

Abstract Objectives This review aims to provide a comprehensive examination of biomarkers and interdisciplinary variables related to aging. Methods This scoping review included studies which involved adult participants, and which reported on the relationship between any biomarker or biological age with chronological age. Results After screening, 447 articles met the selection criteria. Results were categorized into 10 distinct categories through an iterative process. Conclusions This review contributes information regarding the interdisciplinary influences on the rate of aging. Telomere length was the most commonly examined biomarker, and Horvath’s 353-CpG Pan-Tissue clock was the most common clock, with both demonstrating a strong and consistent relationship with chronological age. The interdisciplinary variables demonstrated relationships with biological aging with varying strengths and consistencies.