Megalobrama amblycephala

1. Nicotinamide riboside increases hepatic NAD+ content in M. amblycephala.

   “Moreover, an oral gavage test confirmed that NR presented the most potent effect in increasing hepatic NAD+ content and the NAD+/NADH ratio among four NAD+ precursors.”

   Animalsliver

   The Effectiveness of Four Nicotinamide Adenine Dinucleotide (NAD⁺) Precursors in Alleviating the High-Glucose-Induced Damage to Hepatocytes in Megalobrama amblycephala: Evidence in NAD⁺ Homeostasis, Sirt1/3 Activation, Redox Defense, Inflammatory Response, Apoptosis, and Glucose Metabolism

   Antioxidants (Basel, Switzerland)·22 Mar 2024

2. Nicotinamide riboside decreases inflammation in M. amblycephala cells.

   “NR presented distinct and superior effects in terms of anti-oxidative stress, inflammation inhibition, and anti-apoptosis compared with NA, NAM, and NMN.”

   Cellshigh glucosehepatocyte

   The Effectiveness of Four Nicotinamide Adenine Dinucleotide (NAD⁺) Precursors in Alleviating the High-Glucose-Induced Damage to Hepatocytes in Megalobrama amblycephala: Evidence in NAD⁺ Homeostasis, Sirt1/3 Activation, Redox Defense, Inflammatory Response, Apoptosis, and Glucose Metabolism

   Antioxidants (Basel, Switzerland)·22 Mar 2024

3. Nicotinamide riboside activates NAD+ metabolism in M. amblycephala cells.

   “NR, which also had the most potent NAD+ boosting capacity and a significant Sirt1/3 activation effect.”

   Cellshigh glucosehepatocyte

   The Effectiveness of Four Nicotinamide Adenine Dinucleotide (NAD⁺) Precursors in Alleviating the High-Glucose-Induced Damage to Hepatocytes in Megalobrama amblycephala: Evidence in NAD⁺ Homeostasis, Sirt1/3 Activation, Redox Defense, Inflammatory Response, Apoptosis, and Glucose Metabolism

   Antioxidants (Basel, Switzerland)·22 Mar 2024

4. Nicotinamide riboside increases cell viability in M. amblycephala cells.

   “The NAD+ precursors all improved cell viability, with the maximal effect observed in NR”

   Cellshigh glucosehepatocyte

   The Effectiveness of Four Nicotinamide Adenine Dinucleotide (NAD⁺) Precursors in Alleviating the High-Glucose-Induced Damage to Hepatocytes in Megalobrama amblycephala: Evidence in NAD⁺ Homeostasis, Sirt1/3 Activation, Redox Defense, Inflammatory Response, Apoptosis, and Glucose Metabolism

   Antioxidants (Basel, Switzerland)·22 Mar 2024

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