Youthful brain-derived extracellular vesicles

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Outcomes

4

Angiogenesis

upin rats1

1 study
  1. Youthful brain-derived extracellular vesicles increase angiogenesis in rats.

    “encouraging collagen deposition, angiogenesis, epidermal and dermal regeneration, and folliculogenesis”

    Animalsskin

    Youthful Brain-Derived Extracellular Vesicle-Loaded GelMA Hydrogel Promotes Scarless Wound Healing in Aged Skin by Modulating Senescence and Mitochondrial Function

    Research (Washington, D.C.)28 Mar 2025

More on Angiogenesis

Inflammation

downin cells1

1 study
  1. Youthful brain-derived extracellular vesicles decrease inflammation in cells.

    “YBEVs reduce the expression of senescence, senescence-associated secretory phenotypes, and inflammation-associated proteins, and even restore dysfunction in senescent cells.”

    Cellsin senescent cells

    Youthful Brain-Derived Extracellular Vesicle-Loaded GelMA Hydrogel Promotes Scarless Wound Healing in Aged Skin by Modulating Senescence and Mitochondrial Function

    Research (Washington, D.C.)28 Mar 2025

More on Inflammation

Cellular senescence

downin cells1

1 study
  1. Youthful brain-derived extracellular vesicles decrease cellular senescence in cells.

    “YBEVs reduce the expression of senescence, senescence-associated secretory phenotypes, and inflammation-associated proteins”

    Cellsin senescent cells

    Youthful Brain-Derived Extracellular Vesicle-Loaded GelMA Hydrogel Promotes Scarless Wound Healing in Aged Skin by Modulating Senescence and Mitochondrial Function

    Research (Washington, D.C.)28 Mar 2025

More on Cellular senescence

Wound healing

upin rats1

1 study
  1. Youthful brain-derived extracellular vesicles improve wound healing in rats.

    “YBEV-containing composite hydrogels accelerated scarless wound healing in skin wounds of aged rats.”

    Animalsin aged rats with skin woundsskin

    Youthful Brain-Derived Extracellular Vesicle-Loaded GelMA Hydrogel Promotes Scarless Wound Healing in Aged Skin by Modulating Senescence and Mitochondrial Function

    Research (Washington, D.C.)28 Mar 2025

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