Young fibroblast-derived exosomes

2 papers6 findings

Outcomes

Wound healing

upin animals1upin mice1

2 studies

Young fibroblast-derived exosomes improve wound healing.
“The Y-EXOs@HAMA/PVA MNP shows an excellent influence on delayed wound healing of aged skin with active A-FBs, more deposition of collagen and less production of IL-17A”
Animalsin aged skin wound healing
Highly Active Frozen Nanovesicles Microneedles for Senile Wound Healing via Antibacteria, Immunotherapy, and Skin Regeneration
Advanced healthcare materialsJan 23, 2024
Young fibroblast-derived exosomes improve wound healing in mice.
“Supplementing wounds with exosomes isolated from young mouse wound-edge fibroblasts (exosomesYoung) significantly improved the abundance of myofibroblasts and wound healing in aged mice”
Animals
Young fibroblast-derived exosomal microRNA-125b transfers beneficial effects on aged cutaneous wound healing
Journal of nanobiotechnologyMar 19, 2022

Extracellular matrix remodelling

upin animals1

1 study

Young fibroblast-derived exosomes increase extracellular matrix remodelling.
“more deposition of collagen and less production of IL-17A compared with application of aged fibroblast-derived exosomes (A-EXOs).”
Animalscompared with application of aged fibroblast-derived exosomes
Highly Active Frozen Nanovesicles Microneedles for Senile Wound Healing via Antibacteria, Immunotherapy, and Skin Regeneration
Advanced healthcare materialsJan 23, 2024

IL-17A

downin animals1

1 study

Young fibroblast-derived exosomes decrease IL-17A.
“more deposition of collagen and less production of IL-17A compared with application of aged fibroblast-derived exosomes (A-EXOs).”
Animalscompared with application of aged fibroblast-derived exosomes
Highly Active Frozen Nanovesicles Microneedles for Senile Wound Healing via Antibacteria, Immunotherapy, and Skin Regeneration
Advanced healthcare materialsJan 23, 2024