Young cancer-associated fibroblasts

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funder: National Institute on Aging
  • Animals1

Outcomes

2

Immune response

upin mice1

1 study
  1. Young cancer-associated fibroblasts improve immune response in mice.

    “revitalizing the aged tumor stroma with young CAFs restores immune infiltration and attenuates metastasis in older hosts”

    Animalsheterochronic co-implantation in older hosts

    The Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer

    Cancer research7 Nov 2025

More on Immune response

Metastasis

downin mice1

1 study
  1. Young cancer-associated fibroblasts decrease metastasis in mice.

    “revitalizing the aged tumor stroma with young CAFs restores immune infiltration and attenuates metastasis in older hosts”

    Animalsheterochronic co-implantation in older hosts

    The Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer

    Cancer research7 Nov 2025

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