Withanolide a

1. Withanolide a prevents cellular senescence in cells.

   “It also modulates heat shock protein 90, preventing premature HSC senescence while maintaining genomic stability through enhanced DNA repair mechanisms.”

   Cellspremature HSC senescencehematopoietic stem cells

   Ashwagandha Withanolide-A for HSC Telomerase Protection

   Zenodo (CERN European Organization for Nuclear Research)·28 Apr 2026Preprint

More on Cellular senescence

1. Withanolide a increases telomerase activity in cells.

   “Withanolide-A from Withania somnifera upregulates TERT expression and enhances telomerase activity specifically in hematopoietic stem cells.”

   Cellshematopoietic stem cells

   Ashwagandha Withanolide-A for HSC Telomerase Protection

   Zenodo (CERN European Organization for Nuclear Research)·28 Apr 2026Preprint

More on Telomerase activity

1. Withanolide a increases TERT expression in cells.

   “Withanolide-A from Withania somnifera upregulates TERT expression”

   Cellshematopoietic stem cells

   Ashwagandha Withanolide-A for HSC Telomerase Protection

   Zenodo (CERN European Organization for Nuclear Research)·28 Apr 2026Preprint

More on TERT expression