Vitamin D deficiency

1. Vitamin D deficiency increases cellular senescence in rats.

   “In aged diabetic rats, vitamin D deficiency aggravated hyperglycemia, insulin resistance, intramuscular lipid accumulation, and muscle senescence”

   Animalsaged diabetic ratsgastrocnemius muscle

   Vitamin D status and sarcopenia in older adults: population-based evidence for synergy with diabetes and experimental validation in an aged diabetic rat model

   The journal of nutrition, health & aging·3 Jun 2026

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1. Vitamin D deficiency increases rate of ageing in humans.

   “Not only will this increase the rate of ageing, but it will also increase the probability of developing age-related diseases”

   Review

   Vitamin D deficiency accelerates ageing and age-related diseases: a novel hypothesis

   The Journal of physiology·31 Oct 2017

1. Vitamin D deficiency raises the risk of cardiovascular-kidney-metabolic syndrome in humans (OR 1.32, 95% CI 1.03-1.69).

   “stage 1, 1.32 (1.03-1.69)”

   Humanscompared with vitamin D sufficiency

   Association between Serum 25-Hydroxyvitamin D and Cardiovascular–Kidney–Metabolic Syndrome

   ADA Scientific Sessions 2026 abstract·5 Jun 2026

More on Cardiovascular-kidney-metabolic syndrome

1. Vitamin D deficiency raises the risk of sarcopenia in humans.

   “Low 25(OH)D was associated with higher odds of sarcopenia overall.”

   Humansoverall cohortn = 7,520

   Vitamin D status and sarcopenia in older adults: population-based evidence for synergy with diabetes and experimental validation in an aged diabetic rat model

   The journal of nutrition, health & aging·3 Jun 2026

More on Sarcopenia

1. Vitamin D deficiency raises the risk of stroke in humans (18.5% increased odds).

   “Vitamin D deficient women had 18.5% increased odds of CVA.”

   Humansfemales

   Vitamin D Deficiency Is Associated With Increased Risk of Atrial Fibrillation in Black Women

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

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1. Vitamin D deficiency raises the risk of atrial fibrillation in humans (15.6% vs. 13.7%).

   “Among 13.4 million hospitalizations (weighted to 67 million), AF was more common in women with vitamin D deficiency (15.6%) vs. those without (13.7%).”

   Humansfemales

   Vitamin D Deficiency Is Associated With Increased Risk of Atrial Fibrillation in Black Women

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

More on Atrial fibrillation

1. Vitamin D deficiency raises the risk of Alzheimer's disease in humans.

   “increase the probability of developing age-related diseases such as Alzheimer's disease, Parkinson's disease, multiple sclerosis and cardiovascular disease”

   Review

   Vitamin D deficiency accelerates ageing and age-related diseases: a novel hypothesis

   The Journal of physiology·31 Oct 2017

More on Alzheimer's disease