Vincristine
- 1 lab in 1 country
- Funders: Hoshi University and 1 more
- Animals1
- Cells1
Outcomes
2Extracellular matrix remodelling
downin mice1
1 study
Extracellular matrix remodelling
downin mice1
Vincristine inhibits extracellular matrix remodelling in mice.
“pronounced downregulation of Col1a1, Col1a2, Col3a1, and Eln at both the mRNA and protein levels.”
Animalsskin
Toxicology and applied pharmacology20 Aug 2025
Dermal thickness
downin mice1
1 study
Dermal thickness
downin mice1
Vincristine decreases dermal thickness in mice.
“dermal thinning was observed exclusively in the cisplatin and vincristine.”
Animalsskin
Toxicology and applied pharmacology20 Aug 2025
Latest
Toxicology and Applied Pharmacology
Downregulation of collagen and elastin genes in murine skin following cisplatin and vincristine treatment
Experiments in miceSkin
Journal of Cell Communication and Signaling
Favorable and poor prognosis B-cell precursor acute lymphoblastic leukemia subtypes reveal distinct leukemic cell properties when interacting with mesenchymal stem cells, differentially modifying their cell stemness and leukemia chemoresistance
Experiments in human cellsBlood and immune system
ACS Chemical Neuroscience
Insights into Vincristine-Induced Peripheral Neuropathy in Aged Rats: Wallerian Degeneration, Oxidative Damage, and Alterations in ATPase Enzymes
Experiments in animalsMechanisms
Frontiers in Immunology
Identification of a novel senescence-associated signature to predict biochemical recurrence and immune microenvironment for prostate cancer
Computational studyBiomarkers
Neurobiology of Pain
An adolescent rat model of vincristine-induced peripheral neuropathy
Experiments in animalsInterventions