B-cell acute lymphoblastic leukemia

Disease1 paper1 finding

Human trial1

Associations

1

TP53

upin humans1

1 study

TP53 is associated with B-cell acute lymphoblastic leukemia in humans.
Humansinferior outcome to chemotherapy in older adultsn = 569
Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia - the ECOG-ACRIN E1910 study · Blood · 5 Oct 2026

Trial sponsors

Merck Sharp & Dohme LLC
Company1 trialPhase 2/3340 people
BeOne Medicines
Company1 trialPhase 1/230 people
Institute of Hematology & Blood Diseases Hospital, China
2 trialsPhase 2/34,800 people
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
1 trialPhase 1/218 people
Dana-Farber Cancer Institute
1 trialPhase 123 people

Latest

2

BloodHuman trial5 Oct

Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia - the ECOG-ACRIN E1910 study

HemaSphereIn silico15 Sep

The machine-learning classifier ALLCatchR2 identifies 20 T-ALL subtypes across cohorts and age groups

Machine learning