Total diet replacement
Intervention1 paper3 findings
- Human trial1
Outcomes
3Binge eating scores
downin humans1Very low certainty
1 study
Binge eating scores
downin humans1Very low certainty
Total diet replacement decreases binge eating scores in humans (-4 (-6.5, -0.8)).
Human trial12 monthsfemales
Adherence and weight loss with a total diet replacement programme for increased cancer risk associated with obesity: a UK cohort study · BMJ open · 28 Sep 2026
Quality of life
upin humans1Very low certainty
1 study
Quality of life
upin humans1Very low certainty
Total diet replacement improves quality of life in humans (EQ5D 1 (0, 2)).
Human trial12 monthsfemales
Adherence and weight loss with a total diet replacement programme for increased cancer risk associated with obesity: a UK cohort study · BMJ open · 28 Sep 2026
Body weight
downin humans1Very low certainty
1 study
Body weight
downin humans1Very low certainty
Total diet replacement decreases body weight in humans (-8.4 kg (-13.9, -3.7) at 12 months).
Human trial12 monthsfemalesn = 47
Adherence and weight loss with a total diet replacement programme for increased cancer risk associated with obesity: a UK cohort study · BMJ open · 28 Sep 2026