Tanshinol

1. Tanshinol inhibits cellular senescence in rats.

   “Moreover, Aucubin or Tanshinol treatment reduced IL-1β, TNF-α, P16, and P19 mRNA and protein expression, suppressed p65 phosphorylation, and decreased β-catenin protein contents within IDD samples.”

   Animalsin IDD ratsnucleus pulposus

   Aucubin and Tanshinol from Bu-Shen-Huo-Xue-Fang (BSHXF) improve intervertebral disc degeneration through affecting nucleus pulposus cell

   Journal of molecular histology·May 25, 2026

More on Cellular senescence

1. Tanshinol decreases intervertebral disc degeneration in rats.

   “In IDD rats, Aucubin or Tanshinol treatment also remarkably relieved degenerative alterations.”

   Animalsin IDD rats

   Aucubin and Tanshinol from Bu-Shen-Huo-Xue-Fang (BSHXF) improve intervertebral disc degeneration through affecting nucleus pulposus cell

   Journal of molecular histology·May 25, 2026

More on Intervertebral disc degeneration