Tam-gm@met

1 paper1 finding

1 lab in 1 country

Funders: Chongqing Medical University and 3 more

Animals1

Outcomes

1

Bone loss

downin mice1

1 study

Tam-gm@met decreases bone loss in mice.
“This delivery system effectively upregulated NRF2/IRE1α-dependent UPR signaling, suppressed SASP in vitro, and alleviated bone loss in a mouse model of aging-related periodontitis.”
AnimalsMouse model of aging-related periodontitisSenescence-targeted, metformin-releasing nanocomposite hydrogelbone
Metformin alleviates aging-associated periodontitis via NRF2-mediated restoration of the IRE1α dependent unfolded protein response
Bioactive materials9 Apr 2026

Latest

1 in 12 months

Bioactive Materials20 Apr

Metformin alleviates aging-associated periodontitis via NRF2-mediated restoration of the IRE1α dependent unfolded protein response

Experiments in miceMetformin