In 3,432,327 adults with type 2 diabetes followed for a mean of 9.2 years, six medication categories were associated with a lower risk of aortic aneurysm.In 3,432,327 adults with type 2 diabetes followed for a mean of 9.2 years, six medication categories were associated with a lower risk of aortic aneurysm.
Crude rates of hospitalization or death were 18.6 per 100 person-years with GLP-1 drugs against 16.7 with other diabetes drugs, with an adjusted hazard ratio of 1.05.Crude rates of hospitalization or death were 18.6 per 100 person-years with GLP-1 drugs against 16.7 with other diabetes drugs, with an adjusted hazard ratio of 1.05.
Median age at diagnosis rose from 63.0 years in 2005–2008 to 66.7 years in 2020–2023, alongside more coexisting illnesses and lower blood sugar.Median age at diagnosis rose from 63.0 years in 2005–2008 to 66.7 years in 2020–2023, alongside more coexisting illnesses and lower blood sugar.
Over a median two years, major adverse cardiovascular events occurred in 4.2% of orforglipron participants compared with 5.0% of insulin glargine controls.Over a median two years, major adverse cardiovascular events occurred in 4.2% of orforglipron participants compared with 5.0% of insulin glargine controls.
Bodyweight fell by up to 18.8% with weekly retatrutide compared with 5.1% on placebo at week 80 in adults with obesity and type 2 diabetes.Bodyweight fell by up to 18.8% with weekly retatrutide compared with 5.1% on placebo at week 80 in adults with obesity and type 2 diabetes.