Socioeconomic disadvantage

2 papers1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: GlaxoSmithKline and 2 more

Humans2

Outcomes

Pace of Aging

upin humans1+10% faster

1 study

Socioeconomic disadvantage increases Pace of Aging in humans (10% faster).
“Those who experienced disadvantaged socioeconomic conditions from childhood to adulthood aged 10% faster over the 11 years of follow-up”
Humansconsistently disadvantaged vs advantaged from childhood to adulthood11 years
Associations Between Life-Course Socioeconomic Conditions and the Pace of Aging
The journals of gerontology. Series A, Biological sciences and medical sciences21 Nov 2022