AgingResearch.NewsJoin free

Smart hydrogel

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Hebei Provincial Key Research Projects and 1 more
  • Animals1

Outcomes

2

Cellular senescence

downin animals1downin cells1

1 study

  1. Smart hydrogel prevents cellular senescence in cells.

    “This controlled release reduced reactive oxygen species (ROS) accumulation, maintained a favorable redox balance, promoted autophagy, prevented bone marrow mesenchymal stem cells (BMSCs) senescence, and enhanced osteogenesis.”

    Cellsin vitrobone marrow mesenchymal stem cells

    Versatile smart hydrogels for spatiotemporal drug delivery to orchestrate diabetic bone regeneration

    Bioactive materials28 Oct 2025

  2. Smart hydrogel decreases cellular senescence.

    “In vivo, it enhanced angiogenesis, osteogenesis, and tissue remodeling while reducing cellular senescence in diabetic bone defects.”

    Animalsin diabetic bone defects

    Versatile smart hydrogels for spatiotemporal drug delivery to orchestrate diabetic bone regeneration

    Bioactive materials28 Oct 2025

More on Cellular senescence

Bone regeneration

upin animals1

1 study

  1. Smart hydrogel improves bone regeneration.

    “In vivo, it enhanced angiogenesis, osteogenesis, and tissue remodeling while reducing cellular senescence in diabetic bone defects.”

    Animalsin diabetic bone defects

    Versatile smart hydrogels for spatiotemporal drug delivery to orchestrate diabetic bone regeneration

    Bioactive materials28 Oct 2025

Latest

Related