Sleep disturbances

Exposure

3 papers4 findings

  • 3 independent labs in 2 countries
  • Funders: National Natural Science Foundation of China and others
  • Humans2

Outcomes

2

Gut dysbiosis

upin humans1

1 study
  1. Sleep disturbances induce gut dysbiosis in humans.

    “sleep disturbances induce gut dysbiosis, compromise intestinal barrier integrity-a vulnerability exacerbated by ageing-and alter microbial metabolite production”

    Reviewin ageing

    Unlocking the Gut-Brain-Heart Axis: Mechanistic insights and therapeutic avenues for sleep and cardiovascular comorbidity

    Ageing research reviews10 Apr 2026

Language function

downin humans1

1 study
  1. Sleep disturbances impair language function in humans.

    “In the ADNI cohort, elderly individuals with SD exhibited worse language function compared to those with normal sleep, and this finding was validated in the CLAS and CLHLS cohorts.”

    Humansnon-demented

    Sleep disturbances and language function impairment in the elderly: Evidence of limbic and prefrontal tracts involvement

    Journal of Alzheimer's disease : JAD3 Jul 2025

Associations

2

Language function decline

upin humans1

1 study
  1. Sleep disturbances are associated with language function decline in humans.

    “Meanwhile, the decline in longitudinal language function among elderly individuals with SD occurred at a faster rate.”

    Humansnon-demented

    Sleep disturbances and language function impairment in the elderly: Evidence of limbic and prefrontal tracts involvement

    Journal of Alzheimer's disease : JAD3 Jul 2025

Dementia

upin humans1

1 study
  1. Sleep disturbances raise the risk of dementia in humans (PAF 3.0% (95% CI, 1.8% to 3.8%)).

    “The PAF of later life sleep disturbances was 3.0% (95% CI, 1.8% to 3.8%).”

    Humans

    Potentially Modifiable Dementia Risk Factors in Canada: An Analysis of Canadian Longitudinal Study on Aging with a Multi-Country Comparison

    The journal of prevention of Alzheimer's disease1 Jan 2024

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