SIRT6 activator
SIRT6 activator has been studied in 3 papers since 2022: none in people yet, 3 in animals. The research so far is in animals. The newest paper, Dec 10, 2024: “The deacetylase SIRT6 reduces amyloid pathology and supports cognition in mice by reducing the stability of APP in neurons”.
3 papers study it1 findingUpdated
- 1 lab in 1 country
- Funders: Chonbuk National University and 2 more
- Animals3
What did studies of SIRT6 activator find?
1Studies of SIRT6 activator measured 1 outcome; the most studied are exercise endurance (1 study).
Exercise endurance
upin mice1
1 study
Exercise endurance
upin mice1
SIRT6 activator improves exercise endurance in mice.
“mice treated with an activator of Sirt6 showed an increase in exercise endurance as compared to exercise-trained controls.”
Animalscompared to exercise-trained controls
Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression
Nature communications
Latest
Science Signaling
The deacetylase SIRT6 reduces amyloid pathology and supports cognition in mice by reducing the stability of APP in neurons
Experiments in miceInterventions
Molecular Therapy
Sirt6 protects retinal ganglion cells and optic nerve from degeneration during aging and glaucoma
Experiments in miceGlaucoma
Nature Communications
Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression
Experiments in miceInterventions