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SIRT1-ACTIVATING compound

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Fondation pour la Recherche Médicale and 4 more
  • Animals1

Outcomes

1

Neurodegenerative disease

downin mice1

1 study

  1. SIRT1-ACTIVATING compound prevents neurodegenerative disease in mice.

    “oral administration of a SIRT1-activating compound essentially replicated the beneficial effects of CR.”

    Animalsin a transgenic mouse model of neurodegenerationoral administration

    A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration

    The Journal of neuroscience : the official journal of the Society for Neuroscience22 May 2013

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