Sexual experience

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Associations

Plasma proteomic age

downin humans1

1 study

Sexual experience is associated with plasma proteomic age in humans.
“we observed an association between sexual experience and a 'younger' plasma proteomic age of several cell types, including hepatocytes.”
Humansplasma
Lifelong mating reshaped liver aging in short-lived killifish
bioRxiv13 Oct 2026Preprint

Latest

1 in 12 months

bioRxiv1 h

Lifelong mating reshaped liver aging in short-lived killifish

In killifish experiments, lifelong mating reduced inflammation in old females’ main liver cells, while models based on gene activity predicted “younger” ages for several…In killifish experiments, lifelong mating reduced inflammation in old females’ main liver cells, while models based on gene activity predicted “younger” ages for several liver cell types.

Preprint: experiments in killifishInterventions

Paper

Sexual experience

Associations

Latest

Lifelong mating reshaped liver aging in short-lived killifish

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