Selective estrogen receptor modulators

1. Selective estrogen receptor modulators lower the risk of fractures in humans.

   “In postmenopausal women, both HRT and selectiveestrogen receptor modulators (SERMs) effectively reduce fracture risk and support bone health.”

   Reviewin postmenopausal womenfemales

   Impact of estroprogestin therapies on bone health from adolescence to postmenopause

   Journal of endocrinological investigation·18 Feb 2026

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