Reproductive age
Reproductive age has been studied in 1 paper since 2025: 1 observational study in people. The newest paper, Oct 25, 2025: “Age-related changes in mitochondrial markers and telomere dynamics during initial growth of human preantral follicles”.
1 paper studies it4 findingsUpdated
“Mitochondrial mass (TOMM20) in the follicle pool was stable across age groups, but increased significantly during early follicle growth in younger patients (p < 0.01).”
None of its findings points the other way.
- 1 lab in 1 country
- Funders: China Scholarship Council - University of Melbourne PhD Scholarship and 1 more
- Humans1
What did studies of Reproductive age find?
1Studies of Reproductive age measured 1 outcome; the most studied are telomerase subunit expression (1 study).
Telomerase subunit expression
no changein humans1
1 study
Telomerase subunit expression
no changein humans1
Reproductive age was not clearly linked with telomerase subunit expression in humans (no significant difference by age or follicle size).
“Telomerase subunit expression was detected in preantral follicles without any significant age or size differences.”
Humansno significant difference by age or follicle sizepreantral folliclesfemales
Journal of assisted reproduction and genetics
What is Reproductive age linked with?
3Studies link Reproductive age with 3 measures, most often telomere length during follicle growth (1 study), reactive oxygen species during follicle growth (1) and mitochondrial mass during early follicle growth (1).
Telomere length during follicle growth
upin humans1
1 study
Telomere length during follicle growth
upin humans1
Reproductive age is associated with telomere length during follicle growth in humans (increase during growth in younger age groups; stable in primordial follicles).
“Telomere length was stable in granulosa cells and oocytes within primordial follicles, but increased during growth in younger age groups.”
Humansincrease during growth in younger age groups; stable in primordial folliclesgranulosa cells and oocytesfemales
Journal of assisted reproduction and genetics
Reactive oxygen species during follicle growth
downin humans1
1 study
Reactive oxygen species during follicle growth
downin humans1
Reproductive age is associated with reactive oxygen species during follicle growth in humans (lower ROS in younger subjects compared with other age groups).
“with younger subjects exhibiting lower ROS levels during follicle growth (p < 0.01) than other age groups”
Humanslower ROS in younger subjects compared with other age groupspreantral folliclesfemales
Journal of assisted reproduction and genetics
Mitochondrial mass during early follicle growth
upin humans1
1 study
Mitochondrial mass during early follicle growth
upin humans1
Reproductive age is associated with mitochondrial mass during early follicle growth in humans (increase seen in younger patients (20–26 years)).
“Mitochondrial mass (TOMM20) in the follicle pool was stable across age groups, but increased significantly during early follicle growth in younger patients (p < 0.01).”
Humansincrease seen in younger patients (20–26 years)preantral folliclesfemales
Journal of assisted reproduction and genetics