Pinocembrin
- 2 independent labs in 1 country
- Funders: National Natural Science Foundation of China and 2 more
- Animals2
Outcomes
6CYP1B1
downin mice1
1 study
CYP1B1
downin mice1
Pinocembrin decreases CYP1B1 in mice.
“an effect mediated primarily through the downregulation of CYP1B1.”
Animalsexperimental periodontitis
International dental journalJul 3, 2026
Periodontitis
downin mice1
1 study
Periodontitis
downin mice1
Pinocembrin protects against periodontitis in mice.
“pinocembrin was found to attenuate senescence of GFs and ameliorate experimental periodontitis in mice”
Animalsligature-induced periodontitis
International dental journalJul 3, 2026
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
Pinocembrin decreases cellular senescence in mice.
“pinocembrin was found to attenuate senescence of GFs and ameliorate experimental periodontitis in mice”
Animalsexperimental periodontitis
International dental journalJul 3, 2026
Inflammation
downin mice1
1 study
Inflammation
downin mice1
Pinocembrin decreases inflammation in mice.
“Notably, Pinocembrin reduced neuronal apoptosis and microglia-induced inflammation in elderly POCD mice.”
Animalsin elderly POCD mice
Molecular neurobiologyJul 7, 2025
Apoptosis
downin mice1
1 study
Apoptosis
downin mice1
Pinocembrin decreases apoptosis in mice.
“Notably, Pinocembrin reduced neuronal apoptosis and microglia-induced inflammation in elderly POCD mice.”
Animalsin elderly POCD micehippocampus
Molecular neurobiologyJul 7, 2025
Cognitive function
upin mice1
1 study
Cognitive function
upin mice1
Pinocembrin improves cognitive function in mice.
“Pinocembrin significantly improved cognitive function in elderly POCD mice, without altering locomotor activity or anxiety-like behaviors.”
Animalsin elderly POCD mice
Molecular neurobiologyJul 7, 2025