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FZD1

Gene

4 papers2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Includes the processes named after it and trials of drugs aimed at it.

  • 2 independent labs in 1 country
  • Funder: National Natural Science Foundation of China
  • Humans2
  • Animals1
  • In silico1

Effects

1

Wnt/β-catenin signalling

is required forin mouse cells1

1 study

  1. FZD1 is required for wnt/β-catenin signalling in mouse cells.

    “while FZD1 knockdown abolished Pinocembrin's effects on microglial M1 polarization and apoptosis. This cascade activated the Wnt/β-catenin pathway”

    Cellsshown by FZD1 knockdown abolishing Pinocembrin's effects

    Pinocembrin Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Modulating miR-384-5p/FZD1 Axis to Activate the Wnt/β-Catenin Pathway

    Molecular neurobiology7 Jul 2025

More on Wnt/β-catenin signalling

Associations

1

Prognosis

upin humans1

1 study

  1. FZD1 predicts prognosis in humans.

    “FZD1 and G6PD are two DR genes that serve as biomarkers for predicting the prognosis of patients with hepatocellular carcinoma.”

    Humansin hepatocellular carcinomalivern = 90

    An integrative pan-cancer analysis of the molecular characteristics of dietary restriction in tumour microenvironment

    EBioMedicine19 Mar 2024

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