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Pharmacological agents

Intervention

2 papers2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Fonds De La Recherche Scientifique - FNRS and 1 more
  • Model organisms1

Outcomes

1

Lifespan

upin B. terrestris1

1 study

  1. Pharmacological agents extend lifespan in B. terrestris.

    “we pharmacologically increased individual lifespan with pharmacological agents”

    Model organismsmales

    Epigenetic age prediction using N6-methyladenine in the bumblebee Bombus terrestris

    bioRxiv (Cold Spring Harbor Laboratory)25 Jun 2025Preprint

Associations

1

Epigenetic age relative to chronological age

downin B. terrestris1

1 study

  1. Pharmacological agents are associated with epigenetic age relative to chronological age in B. terrestris.

    “for individuals whose lifespan had been pharmacologically increased, each clock predicted younger epigenetic age than chronological age”

    Model organismsindividuals whose lifespan had been pharmacologically increasedmales

    Epigenetic age prediction using N6-methyladenine in the bumblebee Bombus terrestris

    bioRxiv (Cold Spring Harbor Laboratory)25 Jun 2025Preprint

More on Epigenetic age relative to chronological age

Funding

1 grant since 2023

Canadian Institutes of Health Research (CIHR) Project GrantCA$17.5k

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