Epigenetic age relative to chronological age

Biomarker

1 paper1 finding

Model organisms1

Associations

Pharmacological agents

downin B. terrestris1

1 study

Pharmacological agents are associated with epigenetic age relative to chronological age in B. terrestris.
“for individuals whose lifespan had been pharmacologically increased, each clock predicted younger epigenetic age than chronological age”
Model organismsindividuals whose lifespan had been pharmacologically increasedmales
Epigenetic age prediction using N6-methyladenine in the bumblebee Bombus terrestris
bioRxiv (Cold Spring Harbor Laboratory)25 Jun 2025Preprint

Latest

2 in 12 months

Neurology Open Access4 Oct

Epigenetic age links to higher dementia risk in older adults

In 2,606 participants, higher DunedinPACE was associated with increased risks of mild cognitive impairment (hazard ratio 1.16) and all-cause dementia (hazard ratio 1.30).In 2,606 participants, higher DunedinPACE was associated with increased risks of mild cognitive impairment (hazard ratio 1.16) and all-cause dementia (hazard ratio 1.30).

Cohort study of 2,606 peopleAll-cause dementia

Paper

Aging Cell5 Dec