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Pegvisomant

Intervention

1 paper1 finding

MeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Cancer Research Trust New Zealand and 2 more
  • Animals1

Outcomes

1

IGF-1

no changein mice1

1 study

  1. Pegvisomant has no effect on IGF-1 in mice.

    “In contrast, amine-PEGylated B2036-PEG5K did not significantly reduce serum IGF-I levels.”

    AnimalsB2036-PEG5K30 mg/kg24 h

    Growth hormone receptor antagonists, GHA2 and GHA3, with dual activity against the human and mouse receptor

    Protein science : a publication of the Protein Society17 Jul 2025

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