GHA2

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Cancer Research Trust New Zealand and 2 more
  • Animals1

Outcomes

1

IGF-1

downin mice1−41%

1 study
  1. GHA2 decreases IGF-1 in mice (-40.7%).

    “A single dose of 30 mg/kg of amine-PEGylated GHA2-PEG5K or site-specific conjugate, GHA3-PEG40K, reduced serum IGF-1 in mice at 24 h by 40.7% and 45.8%, respectively.”

    AnimalsGHA2-PEG5K30 mg/kg24 h

    Growth hormone receptor antagonists, GHA2 and GHA3, with dual activity against the human and mouse receptor

    Protein science : a publication of the Protein Society17 Jul 2025

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