GHA2
1 paper1 finding
- 1 lab in 1 country
- Funders: Cancer Research Trust New Zealand and 2 more
- Animals1
Outcomes
1IGF-1
downin mice1−41%
1 study
IGF-1
downin mice1−41%
GHA2 decreases IGF-1 in mice (-40.7%).
“A single dose of 30 mg/kg of amine-PEGylated GHA2-PEG5K or site-specific conjugate, GHA3-PEG40K, reduced serum IGF-1 in mice at 24 h by 40.7% and 45.8%, respectively.”
AnimalsGHA2-PEG5K30 mg/kg24 h
Protein science : a publication of the Protein Society17 Jul 2025
Latest
Protein Science
Growth hormone receptor antagonists, GHA2 and GHA3, with dual activity against the human and mouse receptor
Experiments in miceInterventions