Obstructive sleep apnea risk

Obstructive sleep apnea risk has been studied in 3 papers since 2023: 3 observational studies in people; 2 in the past year. The newest paper, Nov 2, 2026: “Longitudinal Associations of Sleep Quality, Insomnia Symptoms, and Obstructive Sleep Apnea Risk with Blood Pressure and Hypertension in Women: A 10-Year Follow-Up of the AHA Go Red for Women Strategically Focused Research…”.

Exposure

3 papers study it7 findingsUpdated

1 new paper in 30 daysSee all 3 papers on obstructive sleep apnea risk

At a glance

The findings reach people, from one lab or study. 3 independent labs in 3 countries.

“women at high-risk ≥70 years had a steeper decline in memory (-0.2 [-0.6, 0.1]) and processing speed (+1.0 [0.4, 1.5]).”
Age- and sex-specific associations between obstructive sleep apnea risk and cognitive decline in middle-aged and older adults: A 3-year longitudinal analysis of the Canadian longitudinal study on agingSleep medicine2023doi:10.1016/j.sleep.2023.09.029

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 3 independent labs in 3 countries
  • Funders: New York University Abu Dhabi and 7 more
  • Humans3

What did studies of obstructive sleep apnea risk find?

6

Studies of obstructive sleep apnea risk measured 6 outcomes, among them urine microalbumin, serum creatinine and C-reactive protein.

Urine microalbumin

upin humans1

1 study
  1. Obstructive sleep apnea risk is linked with higher urine microalbumin in humans after multivariable adjustment for sociodemographic, lifestyle and clinical covariates (β = 3.61 mg/dL, 95% CI 1.64-5.60).

    “urine microalbumin (β = 3.61 mg/dL, 95% CI: 1.64, 5.60)”

    Humansafter multivariable adjustment for sociodemographic, lifestyle and clinical covariates

    Exploring the cardiometabolic profile of Emirati adults at risk for obstructive sleep apnea: findings from the UAE healthy future study

    Frontiers in sleep

More on Urine microalbumin

Serum creatinine

upin humans1

1 study
  1. Obstructive sleep apnea risk is linked with higher serum creatinine in humans after multivariable adjustment for sociodemographic, lifestyle and clinical covariates (β = 0.11 mg/dL, 95% CI 0.09-0.13).

    “serum creatinine (β = 0.11 mg/dL, 95% CI: 0.09, 0.13)”

    Humansafter multivariable adjustment for sociodemographic, lifestyle and clinical covariates

    Exploring the cardiometabolic profile of Emirati adults at risk for obstructive sleep apnea: findings from the UAE healthy future study

    Frontiers in sleep

More on Serum creatinine

C-reactive protein

upin humans1

1 study
  1. Obstructive sleep apnea risk is linked with higher C-reactive protein in humans after multivariable adjustment for sociodemographic, lifestyle and clinical covariates (β = 0.14 mg/dL, 95% CI 0.10-0.18).

    “CRP (β = 0.14 mg/dL, 95% CI: 0.10, 0.18)”

    Humansafter multivariable adjustment for sociodemographic, lifestyle and clinical covariates

    Exploring the cardiometabolic profile of Emirati adults at risk for obstructive sleep apnea: findings from the UAE healthy future study

    Frontiers in sleep

More on C-reactive protein

LDL cholesterol

upin humans1

1 study
  1. Obstructive sleep apnea risk is linked with higher LDL cholesterol in humans after multivariable adjustment for sociodemographic, lifestyle and clinical covariates.

    “higher total cholesterol, LDL-C, triglycerides, and ApoB, and lower HDL-C and ApoA (all p < 0.001)”

    Humansafter multivariable adjustment for sociodemographic, lifestyle and clinical covariates

    Exploring the cardiometabolic profile of Emirati adults at risk for obstructive sleep apnea: findings from the UAE healthy future study

    Frontiers in sleep

More on LDL cholesterol

HbA1c

upin humans1

1 study
  1. Obstructive sleep apnea risk is linked with higher HbA1c in humans after multivariable adjustment for sociodemographic, lifestyle and clinical covariates (β = 0.18%, 95% CI 0.14-0.23).

    “intermediate-to-high OSA risk was associated with elevated HbA1c (β = 0.18%, 95% CI: 0.14-0.23)”

    Humansafter multivariable adjustment for sociodemographic, lifestyle and clinical covariates

    Exploring the cardiometabolic profile of Emirati adults at risk for obstructive sleep apnea: findings from the UAE healthy future study

    Frontiers in sleep

More on HbA1c

Processing speed

downin humans1

1 study
  1. Obstructive sleep apnea risk is linked with worse processing speed in humans (+1.0 [95% CI: 0.4, 1.5]).

    “women at high-risk ≥70 years had a steeper decline in memory (-0.2 [-0.6, 0.1]) and processing speed (+1.0 [0.4, 1.5]).”

    Humans3 yearsfemales

    Age- and sex-specific associations between obstructive sleep apnea risk and cognitive decline in middle-aged and older adults: A 3-year longitudinal analysis of the Canadian longitudinal study on aging

    Sleep medicine

What is obstructive sleep apnea risk linked with?

1

Studies link obstructive sleep apnea risk with in-office systolic blood pressure.

In-office systolic blood pressure

upin humans1

1 study
  1. Obstructive sleep apnea risk is associated with in-office systolic blood pressure in humans (High versus low obstructive sleep apnea risk) (In-office SBP β=8.72; in-office DBP β=6.03).

    “Compared with low OSA risk, high OSA risk was associated with higher oSBP (β=8.72; P =0.043) and oDBP (β=6.03; P =0.024).”

    HumansHigh versus low obstructive sleep apnea riskapproximately 10 yearsfemalesn = 90

    Longitudinal Associations of Sleep Quality, Insomnia Symptoms, and Obstructive Sleep Apnea Risk with Blood Pressure and Hypertension in Women: A 10-Year Follow-Up of the AHA Go Red for Women Strategically Focused Research Network

    AHA Scientific Sessions 2026 abstract

More on In-office systolic blood pressure

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 1Sep 2026: 0Oct 2026: 0Nov 2026: 12 papers in 12 months