Normothermic blood perfusion

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: Deutsche Forschungsgemeinschaft and 1 more
  • Animals1

Outcomes

2

Inflammation

upin pigs1

1 study
  1. Normothermic blood perfusion increases inflammation in pigs.

    “the reduction in microvascular endothelial sprouting, and inflammation”

    Animalsin DCD heartsheart4 h

    Transcriptomic Changes in the Myocardium and Coronary Artery of Donation after Circulatory Death Hearts following Ex Vivo Machine Perfusion

    International journal of molecular sciences19 Jan 2024

More on Inflammation

Oxidative stress and ROS signalling

upin pigs1

1 study
  1. Normothermic blood perfusion increases oxidative stress and ROS signalling in pigs.

    “NBP resulted in the upregulation of genes involved in mitochondrial calcium accumulation and ROS production”

    Animalsin DCD heartsheart4 h

    Transcriptomic Changes in the Myocardium and Coronary Artery of Donation after Circulatory Death Hearts following Ex Vivo Machine Perfusion

    International journal of molecular sciences19 Jan 2024

More on Oxidative stress and ROS signalling

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