Neighborhood social cohesion

11 papers12 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

7 independent labs in 2 countries

Humans11

Outcomes

Cognitive function

upin humans1

1 study

Neighborhood social cohesion improves cognitive function in humans.
“only non-Hispanic White participants’ cognitive trajectories benefited from living in socially cohesive neighborhoods, via reduced loneliness.”
Humansin non-Hispanic White participants, via reduced loneliness
Neighborhood Cohesion, Loneliness, and Cognitive Function: Effects of Race and Place
GSA 2025 abstract31 Dec 2025

Loneliness

downin humans1

1 study

Neighborhood social cohesion decreases loneliness in humans.
“neighborhood social cohesion was associated with reduced loneliness only among non-Hispanic White participants.”
Humansin non-Hispanic White participants
Neighborhood Cohesion, Loneliness, and Cognitive Function: Effects of Race and Place
GSA 2025 abstract31 Dec 2025

Cognitive change

no changein humans1

1 study

Neighborhood social cohesion has no effect on cognitive change in humans.
“However, none of these factors were significantly associated with cognitive trajectories over time.”
Humansn = 2,321
Neighborhood and Psychosocial Predictors of Cognitive Function Among Latinos in the United States
GSA 2025 abstract31 Dec 2025

Associations

Cognitive function

upin humans4

4 studies

Neighborhood social cohesion is associated with cognitive function in humans.
“higher neighborhood social cohesion and lower neighborhood physical disorder were related to higher level of cognitive function among individuals with mild pain trajectory”
Humansamong individuals with mild pain trajectory16 yearsn = 6,983
Longitudinal Associations Between Pain Trajectories and Cognitive Function: The Role of Neighborhood Context
GSA 2025 abstract31 Dec 2025
Neighborhood social cohesion is associated with cognitive function in humans (p < 0.001).
“Neighborhood social cohesion was positively associated with baseline cognitive function (p < 0.001)”
Humansn = 2,321
Neighborhood and Psychosocial Predictors of Cognitive Function Among Latinos in the United States
GSA 2025 abstract31 Dec 2025
Neighborhood social cohesion is associated with cognitive function in humans.
“Adjusted models showed that social cohesion, specifically appraising their neighborhood as a good place to live and trusting most people in their neighborhood, was associated with higher cognitive functioning.”
Humansn = 9,412
NEIGHBORHOOD ENVIRONMENT AND COGNITIVE FUNCTION AMONG OLDER ADULTS IN BRAZIL
GSA 2024 abstract31 Dec 2024
Neighborhood social cohesion is associated with cognitive function in humans.
“Adjusted models showed that social cohesion, specifically appraising their neighborhood as a good place to live and trusting most people in their neighborhood, was associated with higher cognitive functioning.”
Humansadjusted modelsn = 9,412
NEIGHBORHOOD ENVIRONMENT AND COGNITIVE FUNCTION AMONG OLDER ADULTS IN BRAZIL
GSA 2024 abstract31 Dec 2024

Multiple chronic conditions burden

upin humans1

1 study

Neighborhood social cohesion is associated with multiple chronic conditions burden in humans.
“Higher social cohesion at baseline and increases in cohesion over time were associated with greater MCC burden.”
HumansBaseline social cohesion and changes over time6 yearsn = 3,389
Neighborhood Social Cohesion, Physical Disorder, and Multiple Chronic Conditions in Older Adults: An Examination of Racial/Ethnic Differences
Journal of aging and health31 Aug 2025

Executive function

upin humans1

1 study

Neighborhood social cohesion is associated with executive function in humans (p <.01).
“better performance on a measure of executive function (p <.01). Reports of more social control was also associated with better executive function (p <.05).”
Humansadjusted for age, sex, race, education, and poverty status70% femalesn = 77
ASSOCIATIONS BETWEEN MEASURES OF HEALTH AND OBJECTIVE AND SUBJECTIVE NEIGHBORHOOD QUALITY
GSA 2024 abstract31 Dec 2024

Insomnia severity

downin humans1

1 study

Neighborhood social cohesion is associated with insomnia severity in humans (p <.05).
“reports of better social cohesion were associated with lower insomnia severity scores (p <.05)”
Humansadjusted for age, sex, race, education, and poverty status70% femalesn = 77
ASSOCIATIONS BETWEEN MEASURES OF HEALTH AND OBJECTIVE AND SUBJECTIVE NEIGHBORHOOD QUALITY
GSA 2024 abstract31 Dec 2024

Physical activity

upin humans1

1 study

Neighborhood social cohesion is associated with physical activity in humans (B=0.70, 95% CI=0.32, 1.09).
“Higher neighborhood socioeconomic affluence (B=0.45, 95% CI=0.07, 0.84) and social cohesion (B=0.70, 95% CI=0.32, 1.09) were associated with higher levels of physical activity.”
Humansamong people with dementian = 3,073
NEIGHBORHOOD ENVIRONMENT AND PHYSICAL ACTIVITY AMONG PERSONS WITH DEMENTIA
GSA 2024 abstract31 Dec 2024

Household activity limitations

downin humans1

1 study

Neighborhood social cohesion is associated with household activity limitations in humans (Coef.= -0.013, p= 0.037).
“household limitations were associated with IC × social cohesion (Coef.= -0.013, p= 0.037)”
Humansinteraction with intrinsic capacityn = 7,494
MODERATING ROLE OF NEIGHBORHOOD CHARACTERISTICS ON INTRINSIC CAPACITY AND FUNCTIONAL LIMITATIONS
GSA 2024 abstract31 Dec 2024