NAT10 inhibitor

Intervention

2 papers1 finding

  • 1 lab in 1 country
  • Funder: Zhejiang University
  • Humans1
  • Model organisms1

Outcomes

1

Colitis

downin mice1

1 study
  1. NAT10 inhibitor protects against colitis in mice.

    “Knockdown of NAT10, treatment with Nat10 or Dyrk1a inhibitor, alleviates colitis in aged mice.”

    Animals

    Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of DYRK1A

    Nature communications1 Mar 2026

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