N-acetylcysteine amide
3 papers4 findings
- 3 independent labs in 4 countries
- Funders: Biomedical Advanced Research and Development Authority and 8 more
- 2 of 4 findings with company ties
- Animals1
- Model organisms1
- Cells1
Outcomes
4Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
N-acetylcysteine amide decreases cellular senescence in human cells.
“NACA exhibited the capacity to mitigate DNA damage and cellular senescence”
Cellsradiation exposure
Liver quad culture chip as a model for radiation injury research
Scientific reports11 Apr 2025
DNA damage
downin human cells1
1 study
DNA damage
downin human cells1
N-acetylcysteine amide decreases DNA damage in human cells.
“NACA exhibited the capacity to mitigate DNA damage and cellular senescence”
Cellsradiation exposure
Liver quad culture chip as a model for radiation injury research
Scientific reports11 Apr 2025
Lens opacity
downin mice1
1 study
Lens opacity
downin mice1
N-acetylcysteine amide decreases lens opacity in mice.
“In ex vivo lens experiments, NACA significantly reduced H2O2-induced lens opacity and preserved lens integrity.”
Animalsin ex vivo lenses exposed to H2O2
Biomolecules19 Mar 2025
Spreading depolarization event duration
downin locust1
1 study
Spreading depolarization event duration
downin locust1
N-acetylcysteine amide decreases spreading depolarization event duration in locust.
“pretreatment with the antioxidant, N-acetylcysteine amide, had opposite effects to those of aging, reducing duration, and increasing rate of recovery”
Model organismsouabain-induced spreading depolarization
Journal of neurophysiology12 Dec 2024