Magnesium-doped bioactive glass

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Outcomes

4

Bone defect repair

upin rats1

1 study
  1. Magnesium-doped bioactive glass improves bone defect repair in rats.

    “20 Mg-BG significantly enhances bone defect repair mediated by replicatively senescent hDPSCs”

    Animalscalvarial defect model mediated by replicatively senescent hDPSCscalvarium

    Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy

    Regenerative biomaterials25 Oct 2025

Stem cell differentiation

upin human cells1

1 study
  1. Magnesium-doped bioactive glass increases stem cell differentiation in human cells.

    “thereby enhancing their osteogenic differentiation potential”

    Cellsreplicatively senescent hDPSCs

    Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy

    Regenerative biomaterials25 Oct 2025

More on Stem cell differentiation

Reactive oxygen species

downin human cells1

1 study
  1. Magnesium-doped bioactive glass decreases reactive oxygen species in human cells.

    “improve mitochondrial function, reduce ROS levels”

    Cellsreplicatively senescent hDPSCs

    Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy

    Regenerative biomaterials25 Oct 2025

More on Reactive oxygen species

Cellular senescence

downin human cells1

1 study
  1. Magnesium-doped bioactive glass decreases cellular senescence in human cells.

    “20 Mg-BG (Mg-BG containing 20 mol% MgO) can effectively reverse the replicative senescence of hDPSCs”

    Cellsreplicative senescence

    Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy

    Regenerative biomaterials25 Oct 2025

More on Cellular senescence

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