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Lrp::flag

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

4

Cellular senescence

downin mice1

1 study

  1. Lrp::flag decreases cellular senescence in mice.

    “overexpression of LRP::FLAG significantly improved various proliferative and anti-ageing associated proteins while causing a concomitant decrease in senescence associated proteins”

    Animals

    37 kDa LRP::FLAG enhances telomerase activity and reduces ageing markers in vivo

    Cellular and molecular life sciences : CMLS22 Feb 2025

More on Cellular senescence

Telomere length

upin mice1

1 study

  1. Lrp::flag increases telomere length in mice.

    “certain organs displayed increased telomerase activity with a corresponding elongation in average telomere length”

    Animals

    37 kDa LRP::FLAG enhances telomerase activity and reduces ageing markers in vivo

    Cellular and molecular life sciences : CMLS22 Feb 2025

More on Telomere length

Tissue degeneration

downin mice1

1 study

  1. Lrp::flag decreases tissue degeneration in mice.

    “markedly less tissue degeneration and atrophy when compared to control and non-treated mice”

    Animals

    37 kDa LRP::FLAG enhances telomerase activity and reduces ageing markers in vivo

    Cellular and molecular life sciences : CMLS22 Feb 2025

Physical function

upin mice1

1 study

  1. Lrp::flag improves physical function in mice.

    “mice overexpressing LRP::FLAG displayed improved physiological characteristics”

    Animals

    37 kDa LRP::FLAG enhances telomerase activity and reduces ageing markers in vivo

    Cellular and molecular life sciences : CMLS22 Feb 2025

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