Low-valine diet

Low-valine diet has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Oct 22, 2026: “Low-valine diet eases heart enlargement in male rodents”.

Intervention

1 paper studies it4 findingsUpdated Oct 21, 2026

None of its findings points the other way.

1 lab in 1 country

Animals1

What did studies of Low-valine diet find?

Studies of Low-valine diet measured 4 outcomes; the most studied are Mitochondrion (1 study), ATP5F1B (1) and cardiac function (1).

Mitochondrion

upin Rodentia1

1 study

Low-valine diet improves mitochondrion in Rodentia.
“Thereby, it alleviates mitochondrial damage, improves mitochondrial function, and sustains mitochondrial homeostasis.”
Animalsin hypertensive animalsheartmales
Low-valine diet eases heart enlargement in male rodents
Nature communicationsOct 21, 2026

ATP5F1B

upin Rodentia1

1 study

Low-valine diet increases ATP5F1B in Rodentia.
“Notably, a low-valine diet reduces the degradation of ATP5F1B mediated by LONP1, and contributes to an increase of ATP5F1B at protein levels.”
Animalsin hypertensive animalsheartmales
Low-valine diet eases heart enlargement in male rodents
Nature communicationsOct 21, 2026

Latest

1 paper in 12 months

Nature CommunicationsOct 22

Low-valine diet eases heart enlargement in male rodents

In hypertensive male rodents, restricting the dietary amino acid valine improved heart function and reduced harmful muscle enlargement by protecting a key mitochondrial…In hypertensive male rodents, restricting the dietary amino acid valine improved heart function and reduced harmful muscle enlargement by protecting a key mitochondrial protein.

Animal studyInterventions

Paper

Low-valine diet

What did studies of Low-valine diet find?

Latest

Low-valine diet eases heart enlargement in male rodents

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