Lactate metabolism reprogramming reactor

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

3

Biomechanical function

upin animals1+94% normal tissues

1 study
  1. Lactate metabolism reprogramming reactor improves biomechanical function (94% of normal tissues).

    “The biomechanical function of neo-generated tissues reaches 94% of that of normal tissues”

    Animalsneo-generated tissues

    Lactate metabolism reprogramming through orthogonal tandem catalysis to reverse intervertebral disc degeneration

    Nature communications7 Apr 2026

Cellular senescence

downin cells1

1 study
  1. Lactate metabolism reprogramming reactor inhibits cellular senescence in cells.

    “significantly inhibiting the inflammatory storm and NPCs senescence”

    Cellsin vitro and in vivo

    Lactate metabolism reprogramming through orthogonal tandem catalysis to reverse intervertebral disc degeneration

    Nature communications7 Apr 2026

More on Cellular senescence

NLRP3 inflammasome

downin cells1

1 study
  1. Lactate metabolism reprogramming reactor inhibits NLRP3 inflammasome in cells.

    “down-regulate lactate to reduce NLRP3 activity”

    Cellsin vitro and in vivo

    Lactate metabolism reprogramming through orthogonal tandem catalysis to reverse intervertebral disc degeneration

    Nature communications7 Apr 2026

More on NLRP3 inflammasome

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