Iron oxide nanoparticles

2 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: National Key Research and Development Program of China and 1 more

Animals2

Outcomes

Autophagy

upin cells1

1 study

Iron oxide nanoparticles activate autophagy in cells.
“functionalized Fe3O4 nanoparticles that enhance donor mitochondrial quality via autophagy activation and Fe-S cluster biogenesis”
Cells
Iron oxide nanoparticles-driven mitochondrial renewal rejuvenates the aged bone marrow niche
Biomaterials12 Jan 2026