Intervention targeting sumoylation

1 paper1 finding

1 lab in 1 country

Animals1

Outcomes

1

Intervertebral disc degeneration

downin rats1

1 study

Intervention targeting sumoylation decreases intervertebral disc degeneration in rats.
“In the rat IDD model, intervention targeting SUMOylation markedly slowed disease progression.”
Animalsrat IDD model
SENP1 mitigates intervertebral disc degeneration: mechanisms involving suppression of pyroptosis and apoptosis in nucleus pulposus cells
Journal of orthopaedic surgery and research11 May 2026

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Journal of Orthopaedic Surgery and Research11 May

SENP1 mitigates intervertebral disc degeneration: mechanisms involving suppression of pyroptosis and apoptosis in nucleus pulposus cells

Experiments in ratsPyroptosis