INTERLEUKIN-6

Intervention

1 paper1 finding

  • Funder: National Institute on Aging

Outcomes

1

Cellular senescence

upin humans1

1 study
  1. INTERLEUKIN-6 induces cellular senescence in humans.

    “IL-6/sIL-6Rα stimulation forms a senescence-inducing circuit involving the STAT3-insulin-like growth factor-binding protein 5 (IGFBP5) as a key axis triggering and reinforcing component in human fibroblasts.”

    Reviewin human fibroblastsfibroblasts

    IL-6-STAT3 signaling and premature senescence

    JAK-STAT22 Jul 2013

More on Cellular senescence

Funding

1 grant since 2023

National Institute on AgingUS$82.7k

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