INTERLEUKIN-6
1 paper1 finding
- Funder: National Institute on Aging
Outcomes
1Cellular senescence
upin humans1
1 study
Cellular senescence
upin humans1
INTERLEUKIN-6 induces cellular senescence in humans.
“IL-6/sIL-6Rα stimulation forms a senescence-inducing circuit involving the STAT3-insulin-like growth factor-binding protein 5 (IGFBP5) as a key axis triggering and reinforcing component in human fibroblasts.”
Reviewin human fibroblastsfibroblasts
IL-6-STAT3 signaling and premature senescence
JAK-STAT22 Jul 2013
Funding
1 grant since 2023National Institute on AgingUS$82.7k