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Inhaled corticosteroids

Inhaled corticosteroids has been studied in 2 papers since 2026: 2 observational studies in people; 2 in the past year. The newest story, Oct 20, 2026: “Inhaled steroids not clearly linked to higher glaucoma risk”.

Intervention

2 papers study it2 findingsUpdated

“ICS prescription was not associated with subsequent MACE in any concurrent CKM-COPD cohort.”
The role of COPD and inhaled corticosteroids in major adverse cardiovascular events in cardiovascular-kidney-metabolic populationsBMC medicine2026doi:10.1186/s12916-026-04754-7

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 1 country
  • Funders: Canadian Institutes of Health Research and 2 more
  • Humans2

What did studies of Inhaled corticosteroids find?

2

Studies of Inhaled corticosteroids measured 2 outcomes; the most studied are open-angle glaucoma (1 study) and major adverse cardiovascular events (1).

Open-angle glaucoma

no changein humans1HR 1.14

1 study

  1. Inhaled corticosteroids have no effect on open-angle glaucoma in humans (HR 1.14, 95% CI 0.94–1.38; no statistically significant association).

    “did not observe a statistically significant increase in the risk of OAG with ICS use”

    HumansPatients with chronic obstructive pulmonary disease; any use since cohort entry compared with non-usen = 84,564

    Inhaled steroids not clearly linked to higher glaucoma risk

    International journal of chronic obstructive pulmonary disease

More on Open-angle glaucoma

Major adverse cardiovascular events

no changein humans1

1 study

  1. Inhaled corticosteroids have no effect on major adverse cardiovascular events in humans.

    “ICS prescription was not associated with subsequent MACE in any concurrent CKM-COPD cohort.”

    Humansin concurrent CKM-COPD cohorts

    The role of COPD and inhaled corticosteroids in major adverse cardiovascular events in cardiovascular-kidney-metabolic populations

    BMC medicine

More on Major adverse cardiovascular events

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 12 papers in 12 months
International Journal of Chronic Obstructive Pulmonary Disease

Inhaled steroids not clearly linked to higher glaucoma risk

The glaucoma hazard ratio, a measure of relative risk, was 1.14 for inhaled steroid use versus non-use in people with chronic obstructive pulmonary disease.The glaucoma hazard ratio, a measure of relative risk, was 1.14 for inhaled steroid use versus non-use in people with chronic obstructive pulmonary disease.

Case-control · 84,564 peopleEye
Paper

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