Icare-hf programme participation

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Humans1

Associations

In-hospital mortality

downin humans1OR 0.87

1 study

Icare-hf programme participation is associated with in-hospital mortality in humans (Adjusted OR 0.87, 95% CI 0.48–1.56; crude mortality 2.3% versus 5.5%).
“Although crude in-hospital mortality was lower in ICARe-HF centres (2.3% vs 5.5%), this association was attenuated after multivariable adjustment (OR=0.87, 95% CI:0.48-1.56).”
HumansMultivariable-adjusted association; exploratoryduring hospitalization
"Baseline Characteristics and Utilization of Medical Therapies in Acute Hospitalized and Chronic Heart Failure Patients Enrolled in GRASP-HF: Differences Between ICARe-HF and Non-ICARe-HF Centres"
European journal of heart failure13 Oct 2026

Quadruple therapy implementation

upin humans1OR 1.73

1 study

Icare-hf programme participation is associated with quadruple therapy implementation in humans (Adjusted OR 1.73, 95% CI 1.17–2.55).
“remained associated with ICARe-HF participation after adjustment, Odd Ratio (OR) =1.73, 95% Confidence Interval (CI) :1.17-2.55.”
HumansHeart failure with reduced ejection fraction; multivariable-adjusted association
"Baseline Characteristics and Utilization of Medical Therapies in Acute Hospitalized and Chronic Heart Failure Patients Enrolled in GRASP-HF: Differences Between ICARe-HF and Non-ICARe-HF Centres"
European journal of heart failure13 Oct 2026

Latest

1 in 12 months

European Journal of Heart FailureYesterday

"Baseline Characteristics and Utilization of Medical Therapies in Acute Hospitalized and Chronic Heart Failure Patients Enrolled in GRASP-HF: Differences Between ICARe-HF and Non-ICARe-HF Centres"

Cohort study of 10,936 peopleHeart failure

Paper

Icare-hf programme participation

Associations

Latest

"Baseline Characteristics and Utilization of Medical Therapies in Acute Hospitalized and Chronic Heart Failure Patients Enrolled in GRASP-HF: Differences Between ICARe-HF and Non-ICARe-HF Centres"

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