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Hydrogel microspheres

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 2 more
  • Animals1

Outcomes

4

Inflammation

downin cells1

1 study

  1. Hydrogel microspheres decrease inflammation in cells.

    “reducing inflammation levels”

    Cellscartilage

    Microenvironment-Responsive Injectable Microspheres for Osteoarthritis Treatment via Oxidative Stress Inhibition and Sustained Lubrication

    Advanced healthcare materials4 Sep 2025

More on Inflammation

Oxidative stress and ROS signalling

downin cells1

1 study

  1. Hydrogel microspheres decrease oxidative stress and ROS signalling in cells.

    “alleviating chondrocyte oxidative stress and restoring mitochondrial function”

    Cellscartilage

    Microenvironment-Responsive Injectable Microspheres for Osteoarthritis Treatment via Oxidative Stress Inhibition and Sustained Lubrication

    Advanced healthcare materials4 Sep 2025

More on Oxidative stress and ROS signalling

Cellular senescence

downin cells1

1 study

  1. Hydrogel microspheres inhibit cellular senescence in cells.

    “inhibiting chondrocyte senescence triggered by oxidative stress”

    Cellstriggered by oxidative stresscartilage

    Microenvironment-Responsive Injectable Microspheres for Osteoarthritis Treatment via Oxidative Stress Inhibition and Sustained Lubrication

    Advanced healthcare materials4 Sep 2025

More on Cellular senescence

Osteoarthritis

downin animals1

1 study

  1. Hydrogel microspheres protect against osteoarthritis.

    “retard the progression of OA in vivo”

    Animalscartilage

    Microenvironment-Responsive Injectable Microspheres for Osteoarthritis Treatment via Oxidative Stress Inhibition and Sustained Lubrication

    Advanced healthcare materials4 Sep 2025

More on Osteoarthritis

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