Human umbilical cord mesenchymal stem cell-derived exosome
1 paper3 findings
- 1 lab in 1 country
- Funders: Guangxi Key Research and Development Program and 2 more
- Animals1
Outcomes
3Body weight
upin mice1
1 study
Body weight
upin mice1
Human umbilical cord mesenchymal stem cell-derived exosome increases body weight in mice.
“treatment of exosomes or metformin improved several aging-related phenotypes in both mouse and cellular models, including increases in body weight, liver and kidney weights”
Animalsdoxorubicin-induced model
Human umbilical cord mesenchymal stem cell-derived exosome ameliorate doxorubicin-induced senescence
Experimental cell research21 Feb 2025
Inflammation
downin mice1
1 study
Inflammation
downin mice1
Human umbilical cord mesenchymal stem cell-derived exosome decreases inflammation in mice.
“hucMSC-Exo resulted in the downregulation of inflammatory factors and senescence markers in liver and kidney tissues as well as cell models.”
Animalsdoxorubicin-induced senescence
Human umbilical cord mesenchymal stem cell-derived exosome ameliorate doxorubicin-induced senescence
Experimental cell research21 Feb 2025
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
Human umbilical cord mesenchymal stem cell-derived exosome decreases cellular senescence in mice.
“reduction of SA-β-Gal positive cells in kidney and skin tissues as well as cell models.”
Animalsdoxorubicin-induced cellular senescence
Human umbilical cord mesenchymal stem cell-derived exosome ameliorate doxorubicin-induced senescence
Experimental cell research21 Feb 2025