Gasdermin d inhibitor
Gasdermin d inhibitor has been studied in 1 paper since 2025: none in people yet, 1 in cells; 1 in the past year. No study of it in people or animals has been published yet. The newest paper, Dec 30, 2025: “Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment”.
1 paper studies it1 findingUpdated
- 1 lab in 1 country
- Funders: HHS | NIH | NHLBI and 7 more
- Cells1
What did studies of Gasdermin d inhibitor find?
1Studies of Gasdermin d inhibitor measured 1 outcome; the most studied are fitness (1 study).
Fitness
downin human cells1
1 study
Fitness
downin human cells1
Gasdermin d inhibitor decreases fitness in p53 mutant HSPCs.
“inhibiting IL-1β secretion using gasdermin D inhibitor decreases the fitness of p53 mutant HSPCs”
Cellsin p53 mutant HSPCs
Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment
The Journal of clinical investigation
Latest
1 paper in 12 monthsThe Journal of Clinical Investigation
Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment
Experiments in human cellsInflammation