F1462
1 paper2 findings
- 1 lab in 1 country
- Funders: Fundamental Research Funds for the Central Universities and 2 more
- Cells1
Outcomes
2Vascular wall thickening
downin mice1
1 study
Vascular wall thickening
downin mice1
F1462 decreases vascular wall thickening in mice.
Animalsin naturally aged mice
European journal of pharmacology20 Aug 2026
Mitochondrial biogenesis (PGC-1α)
upin human cells1
1 study
Mitochondrial biogenesis (PGC-1α)
upin human cells1
F1462 activates mitochondrial biogenesis (PGC-1α) in human cells.
Cellsin a DOX-induced EC senescence model
European journal of pharmacology20 Aug 2026
Latest
1 in 12 monthsEuropean Journal of Pharmacology
Novel SIRT1 up-regulator F1462 attenuates endothelial cell senescence and vascular aging by promoting mitochondrial biogenesis via activating the SIRT1/PGC-1α/TFAM pathway
Experiments in human cellsInterventions