Extracellular vesicles from lipofibroblasts
1 paper4 findings
- 1 lab in 1 country
- Funders: Japan Agency for Medical Research and Development and 1 more
- Animals1
Outcomes
4Stem cell differentiation
downin cells1
1 study
Stem cell differentiation
downin cells1
Extracellular vesicles from lipofibroblasts inhibit stem cell differentiation in cells.
“LipoFB-EVs demonstrate anti-fibrotic properties by inhibiting TGF-β-induced myofibroblast differentiation”
CellsTGF-beta-induced
American journal of respiratory and critical care medicine25 Feb 2026
Cellular senescence
downin cells1
1 study
Cellular senescence
downin cells1
Extracellular vesicles from lipofibroblasts decrease cellular senescence in cells.
“They effectively mitigate key COPD pathologies such as cellular senescence and inflammatory responses in lung epithelial cells.”
Cellsin vitrolung
American journal of respiratory and critical care medicine25 Feb 2026
Alveolar emphysema
downin mice1
1 study
Alveolar emphysema
downin mice1
Extracellular vesicles from lipofibroblasts decrease alveolar emphysema in mice.
“resulted in significant improvements in airway inflammation, remodeling, obstruction, cellular senescence, and alveolar emphysema induced by both short- and long-term CS exposure”
Animalscigarette smoke exposurelung
American journal of respiratory and critical care medicine25 Feb 2026
Airway inflammation
downin mice1
1 study
Airway inflammation
downin mice1
Extracellular vesicles from lipofibroblasts decrease airway inflammation in mice.
“the administration of LipoFB-EVs in murine models of COPD resulted in significant improvements in airway inflammation, remodeling, obstruction, cellular senescence, and alveolar emphysema”
Animalscigarette smoke exposurelung
American journal of respiratory and critical care medicine25 Feb 2026